NEWS
300 12 months of science
Comets, stem cells, cosmic dust and more
304 Images of the year
FEATURES
311 Nature's 10
Who were the people who made a mark in science this year?
NEWS & VIEWS
340 Editors' choice
A round-up of the highlights from this year's News & Views
EDITORIALS
287 SCIENCE & SOCIETY
Keep asking the question
The US Census Bureau should not
abandon data on working scientists
2B7 PUBLISHING Spin cycle
Media hype does science no favours
2B8 CLIMATE CHARGE Honest brokers
The deal struck in Lima is too weak
WORLD VIEW
289 Challenge the abuse of science in setting policy
Guillaume Chapron
Beware politicians misusing data
RESEARCH HIGHLIGHTS
29O SELECTIONS FROM THE SCIENTIFIC LITERATURE Evidence for 'Kamikaze' typhoons / Hailstone dynamics / Indirect neonicotinoid action / Drought claimed Mayan city
SEVEN DAYS
292 THE NEWS IN BRIEF
Protesters damage archaeology / LHC ready for return / US budget passed
295 FIELD REPORT
Local customs present challenges for Ebola control
297 EVOLUTION
Meet the collaboration behind the latest bird family tree
298 POLITICS
Russian scientists divided over Putin's policies
, CAREERS
441 COLUMN
Nurture your online persona
Peter Fiske
The Internet offers contacts and can help you find a job
Your guide to global scientific events and courses in 2015
321 SCIENTIFIC METHOD
Defend the integrity of physics George Ellis & Joe Silk Speculative theories on the Universe need experimental testing
323 INFECTIOUS DISEASE
Mobilizing Ebola survivors to curb the epidemic
Joshua M Epstein, Lauren M Sauer, Julia Chelen, Erez Hatna, Jon Parker, Richard E Rothman & Lewis Rubinson A proposal to alter the dynamics
BOOKS & ARTS 326 IN RETROSPECT
Between Pacific Tides
Aaron Hirsh
CORRESPONDENCE
329 Comets and life / Conservation areas that work / Hungary's grants Body / Flood protection / Peer-review panel
OBITUARY
33O Martin L Perl (1927-2014) Valerie Halyo
FUTURES
444 The chains of plenty S R Algemon
NEW ONLINE
331 Papers published this week at nature.con NEWS & VIEWS
332 ORGANIC SYNTHESIS
Better chemistry through radicals
An iron-catalysed
alkene-coupling reaction
Steven L Castle SEE ARTICLE P.343
333 SYNTHETIC BIOLOGY Toehold gene switches make big footprints A class of riboregulator that can be tailored to desired trigger RNAs
Simon Ausländer & Martin Fussenegger
334 MALARIA
How vector mosquitoes beat the heat Related mosquito species show distinct dry-season survival strategies Nora J Besansky SEE LETTER R387
336 CONSERVATION
Mind the gaps
Global analysis of protected areas and of future gains and threats Thomas M Brooks SEE LETTER P.383
337 MATERIALS SCIENCE
Two steps for a
magnetoelectric switch Reversal of magnetization using an electric field Kathrin Dörr & Andreas Herklotz
SEE LETTER P.370
338 INFLUENZA
An RNA-synthesizing machine Crystal structures of the viral RNA polymerases of influenza A and B Robert M Krug
SEE ARTICLES P.355 & R361
34O EDITORS' CHOICE
The News & Views highlights of 2014
ARTICLES
343 ORGANIC CHEMISTRY Functionalized olefin cross-coupling to construct carbon—carbon bonds
J C Lo et al. SEE N&V P.332
349 BIOCHEMISTeAn AUTS2—Polycomb complex activates gene expression in the CNS
Z Gao et al.
355 VIROLOGY Structure of influenza A polymerase bound to the viral RNA promoter
A Pflug D Guilligay, S Reich &S Cusack SEE N&V R338
36I VIROLOGY Structural insight into cap-snatching and RNA synthesis by influenza polymerase
S Reich et al. SEE N&V P.338
LETTERS
367 ASTROPHYSICS The exclusion of a significant range of ages in a massive star cluster
C Li, R de Grijs & L Deng
37O MATERIALS SCIENCE Deterministic switching of ferromagnetism at room temperature using an electric field J T Heron et al. SEE N&V R337
374 MOLECULAR PHYSICS Reconstruction
and control of a time-dependent two-electron wave packet
C Ottet al.
379 HYDROGEOLOGY The contribution of the Precambrian continental Iithosphere to global H2 production
B Sherwood Lollar, T C Onstott,
G Lacrampe-Couloume & CJ Ballentine
383 CONSERVATJON Global protected area expansion is compromised by projected land-use and parochialism F Montesino Pouzols et al. SEE N&V R336
387 MALARIA Signatures of aestivation and migration in Sahelian malaria mosquito populations
A Dao et al. SEE N&V P.334
39I EVOLUTIONARY DEVELOPMENTAL BIOLOGY A relative shift in cloacal location repositions external genitalia in amniote evolution P Tschopp et al.
395 OBESITY Adenosine activates brown
adipose tissue and recruits beige adipocytes via Am receptors
T Gnad et al.
4O0 STEM CELLS Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
K W McCracken et al.
4O5 STEM OELLS Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells
J Wang et al.
410 CELL BIOLOGY Protein quality control at the inner nuclear membrane A Khmelinskii et al.
414 IMMUNOLOGY Mitochondrial UPRregulated innate immunity provides
resistance to pathogen infection
M W Pellegrino et al.
4I8 IMMUNOLOGY Rapid development of broadly influenza neutralizing antibodies through redundant mutations
L Pappas et al.
423 CANCER In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system
D Maddalo et al.
428 CANCER Rapid modelling of
cooperating genetic events in cancer
through somatic genome editing FJ Sanchez-Rivera et al.
432 MICROBIOLOGY Cohesin-dependent globules and heterochromatin shape genome architecture in S. pombe T Mizuguchi et al.
436 GENETICS R-loops induce repressive chromatin marks over mammalian gene terminators
K Skourti-Stathaki, K Kamieniarz-Gdula & N J Proudfoot
44O ADDENDUM Editorial Expression of
Concern: Non-adaptive origins of interactome complexity
A Fernandez & M Lynch
44O CORRIGENDUM Activation and repression by oncogenic MYC shape tumourspecific gene expression profiles S Walz et al.
nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE
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