EDITORIALS
453 STEM CELLS
Don't rush to rehabilitate Hwang Woo Suk Hwang's return to the scientific stage merits a degree of caution
453 US POLICY
A return to order
With a budget deal finally done, US lawmakers need to avoid another funding hiatus
454 METROLOGY
A question of time
A time reminder of the power
of science
WORLD VIEW
455 Don't stop the quest to measure Big G
Terry Quinn
Pinning down the coupling constant in Newton's law of gravity will be hard, but not impossible
RESEARCH HIGHLIGHTS
456 SELECTIONS FROM THE
SCIENTIFIC LITERATURE
Dopamine and eye disease / Counterproductive antibiotics / Laser-guided particles / Waves powered by climate change / Sweet-seeking mosquitoes
SEVEN DAYS
458 THE NEWS IN BRIEF
Rosetta comet probe phones home / H7N9 fly makes a comeback/ Illumina prepares for $1,000 genome / Sharks face extinction
461 POLICY
US budget finally gets signed into law
463 ANTARCTIC RESEARCH '
Report picks through bones of failed polar-drilling project
464 CARBON CHEMISTRY
Researchers seek ways to boost olivine's carbon-sequestering power
465 ECOLOGY Protected status of Yellowstone's grizzly bears comes under threat
466 EARTH SCIENCE Drilling mission aims to date South China Sea
We need an international effort
backed by governments and l'exiA
commercial interests to save the
seabed ecosystem, say Edward B seit Barbier et al.
477 EDUCATION
Embed social awareness in science curricula
Erin A Cech
Cultural and political context should be integral to science and technology teaching
BOOKS & ARTS
4BO CONSERVATION Rewilding Oz Tim Flannery
4B1 BOOKS IN BRIEF
4B2 DIGITAL DEVELOPMENT Wired cultures John Gilbey
CORRESPONDENCE
4B3 Peer review / Irreproducible results / Soil pollution in China / Soviet croplands / Natural killer cells take an cancer
575 CHARITIES
Profiting from non-profits
The vital link between goal-oriented charities and hands-on researchers
577 TURNING POINT
Marine ecologist Kristin Laidre sees art as well as data in the Arctic
577 CAREER BRIEFS
Can Woo Suk Hwang redeem himself
and rebuild his scientific reputation?
472 QUANTUM PHYSICS Flawed to perfection Synthetic diamonds are paving the way to better quantum computers and biomedical sensors
NEW ONLINE
485 Papers published this week at nature.com
NEWS & VIEWS
4B6 ECOLOGY
Good dirt with good friends Mycorrhizal fungus type regulates amounts of soil organic matter Mark A Bradford SEE LETTER R543
487 SOLAR SYSTEM
Evaporating asteroid
Discovery of water molecules escaping
from the asteroid Ceres
Humberto Campins & Christine M Comfort
SEE LETTER P.525
488 STEM CELLS
Sex specificity in the blood
Oestrogen regulates division frequency of haematopoietic stem cells Dena S Leeman & Anne Brunet
SEE LETTER R555
49O ELECTRONICS
Protecting the weak from the strong A metasurface microwave absorber George V Eleftheriades
491 CLIMATE SCIENCE
A resolution of the Antarctic paradox The Atlantic Ocean may drive changes" in Antarctic winds and sea ice
John King SEE LETTER R538
492 HIV
Not-so-innocent bystanders Abortive HIV-1 infection triggers pyroptosis in CD4' T cells Andrea L Cox & Robert F Siliciano
SEE ARTICLE P.509
J_J 11..J
The intestinal bile acid transporter — now a possible drug target. PAGE 569
ON THE COVER
Power base
Abstract representation of RNA and protein folds in the !arge 39S mammalian mitoribosomal subunit The 3D structure of this subunit provides insights into the changes that have occurred in this ribosome, now specialized for the translation of the very hydrophobic proteins encoded by the mitochondrial genome. PAGE 515
ARTICLES
495 CANCER GENOMICS Discovery and saturation analysis of cancer genes across 21 tumour types
M S Lawrence et al.
502 IMMUNOLOGY Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV
M Roederer et al.
509 IMMUNOLOGY Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection G Doitsh et al. SEE N&V P.492
515 STRUCTURAL BIOLOGY Architecture of the large subunit of the mammalian mitochondrial ribosome
BJ Greber et al.
LETTERS
52O ASTROPHYSICS A millisecond pulsar in a stellar triple system SM Ransom et al.
525 ASTRONOMY Localized sources of water vapour on the dwarf planet (1) Ceres
M Küppers et al. SEE N&V P.487
528 QUANTUM ELECTRONICS Tunable symmetry breaking and helical edge
transport in a graphene quantum spin Hall state
A F Young et al.
533 MATERIALS SCIENCE Dislocations in bilayer graphene
B Butz et al.
538 CLIMATE SCIENCE Impacts of the north and tropical Atlantic Ocean on the Antarctic Peninsula and sea ice X Li, D M Holland, E P Gerber
& C Yoo SEE N&V P.491
543 ECOLOGY Mycorrhiza-mediated competition between plants and decomposers drives soil carbon storage
C Averill, B L Turner
& A C Finzi SEE N&V P.486
546 CROP SCIENCE The genome of the
recently domesticated crop plant sugar beet (Beta vulgaris)
J C Dohm et al.
550 NEUROSCIENCE Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease
C Cruchaga et al.
555 STEM CELLS Oestrogen increases haematopoietic stem-cell selfrenewal in females and during pregnancy
D Nakada et al. SEE N&V P.488 .
559 MICROBIOLOGY Diet rapidly and reproducibly alters the human gut microbiome LA David et al.
564 MOLECULAR BIOLOGY Glutamine methylation in histone H2A is an kNA-polymerase-l-dedicated modification
P Tessarz et al.
569 STRUCTURAL BIOLOGY Structural basis of the alternating-access mechanism in a bile acid transporter
X Zhou et al.
574 RETRACTIDN GIcNAcylation of a histone methyltransferase in retinoic-acidinduced granulopoiesis
R Fujiki et al.
574 CORRIGENDUM Deglacial pulses of deep-ocean Silicate into the subtropical North Atlantic Ocean A N Meckler et al.
nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE
***NEUWERTIG***keine Lesespuren***SEHR SCHÖN***
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- NPG Nature publishing group
- Englische Ausgabe
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