335 CLIMATE CHANGE
Clean up our' skies
Julia Schmale, Drew Shindell,
Erika von Schneidemesser,
Ilan Chabay & Mark Lawrence
Tackle air quality and mitigate climate
change simultaneously
EDITORIALS
311 ADVOCACY
A global vision
The International Council for Science
needs a clear direction to thrive
311 SCIENCE &SOCIETY Save the museums Italy's curators can band together to save threatened collections
312 ANNOUNCEMENT
Data-access practices strengthened Improved links with Scientific Data will make information more accessible
313 Openness in science is key to keeping public trust Mark Yarborough Researchers must actively seek out problems and fix them
RESEARCH HIGHLIChts
314 SELECTIONS FROM THE SCIENTIFIC LITERATURE Mind over genes / Neochromosome an anti-cancer target / Mozartian
laser beams / Spot the leopard
316 THE NEWS IN BRIEF
US and China announce climate plans / Europe axes science-adviser post / PubPeer contests legal action
453 MENTORING AWARDS
Focus on people
Commitment is the watchword for the winners of Nature's annual mentoring award, who this year are from Ireland and Northern Ireland
455 TURNING POINT
Clinical neuroscientist Kate McAllister is keeping in touch in a big way
455 CAREER BRIEFS
International supercomputing centres dedicated to climate prediction are needed to reduce uncertainties
Pursuing the primordial Ted Nield
341 BOOKS IN BRIEF
343 The evolution debate / Primates
in the lab/ Funding ALS research
OBITUARY
344 Allison Doupe (1954-2014)
Thomas R Insel & Story Landis
FUTURES f x3 When the
music ends
Philip Ball
3i0 ASETTA MISSIOP
Philae comet lander's extraordinary 64 hours of science
321 DISASTER RESPONSE
Citizen scientists tapped to make crisis maps more reliable
322 ECOLOGY
Green List highlights conservation success stories
323 GENOMICS
Researchers home in on platinumstandard human genome
324 TECHNOLOGY
US labs Pool resources to
get supercomputer boost
Far-flung physics
The International Centre for Theoretical Physics has helped to train more than 100,000 researchers around the world
NEW ONLINE
345 Papers published this weekat nature.cor NEWS & VIEWS
346 GENOMICS
Mice in the ENCODE Spotlight Comparative analyses of mouse and human genomic regulation
Piero Carninci SEE ARTICLES R355, P.36! R371 & LETTER R402
347 ORIGINS OF LIFE
RNA made in its own mirror image A ribozyme that overcomes enantiomeric cross-inhibition
Sandip A Shelke & Joseph A Piccirilli SEE LETTER P.440
348 MATERIALS PHYSICS
Reactive walls
Domain walls can promote exotic crystallographic phase formation Philippe Ghosez & Jean-Marc Triscone SEE LETTER P.379
35O BIOCHEMISTRY
Succinate strikes
Succinate accumulation contributes to
ischaemic reperfusion injury
Luke A J O'Neill SEE LETTER R431
351 BIOGEOCHEMISTRY
Agriculture and the global
carbon cycle
Intensive crop production affects seasonal flux of atmospheric CO2 Natasha MacBean & Philippe Peylin SEE LETTERS R394 & R398
352 PLANT SCIENCE
Leaf veins share the time of day A circadian clock in the vasculature regulates a clock in the mesophyll Maria C Marti & Alex A R Webb SEE LETTER R419
ARTICLES
355 GENOMICS A comparative encyclopedia of DNA elements in the mouse genome F Yue et al. SEE N&V P.346
365 GENOMICS Conservation of transacting circuitry during mammalian regulatory evolution
A B Stergachis et al. SEE N&V P.346
371 GENOMICS Principles of regulatory information conservation between
This issue of Nature includes four
papers from The Mouse ENCODE
Consortium, providing comprehensive
data on genome regulation in
the premier model organism in
biomedical research.
PAGES 346.355, 365,371 & 402
mouse and human
Y Cheng et al. SEE N&V R346
LETTERS
376 ASTROPHYSICS The power of relativistic Jets is larger than the luminosity of their accretion disks
G Ghisellini, F Tavecchio, L Maraschi, A Celotti & T Sbarrato
379 NANOSCALE MATERIALS Artificial chemical and magnetic structure at the domain walls of an epitaxial oxide S Farokhipoor et al. SEE N&V P.348
384 MATERIALS SCIENCE Approaching disorder-free transport in highmobility conjugated polymers
D Venkateshvaran et al.
389 ORGANIC CHEMISTRY Overcoming the limitations of directed C—H functionalizations of heterocycles Y-J Liu et al.
394 BIOGEOCHEMISTRY Agricultural Green Revolution as a driver of increasing atmospheric CO2 seasonal amplitude N Zeng et al. SEE N&V P.351
39B BIOGEOCHEMISTRY Direct human influence on atmospheric CO2 seasonality from increased
cropland productivity
J M Gray et al. SEE N&V P.351
402 GENOMICS Topologically associating domains are stable units of replication-timing regulation B D Pope et al. SEE N&V P. 346
406 EVOLUTION The drivers of tropical speciation
B T Smith et al.
410 ECOLOGY lndividual improvements and selective mortality shape lifelong migratory performance
F Sergio et al.
414 NEUROSCIENCE Synaptic
dysregulation in a human iPS cell model of mental disorders Z Wen et al.
419 PLANT SCIENCE Tissue-specific clocks in Arabidopsis Show asymmetric coupling
M Endo, H Shimizu, M A Nohales,
T Araki &S A Kay SEE N&V P.352
423 MICROBIOLOGY Members of the human
gut microbiota involved in recovery from Vibrio cholerae infection
A Hsiao et al.
427 IMMUNOLOGY Structure of malaria Invasion protein RH5 with erythrocyte basigin and blocking antibodies
K E Wright et al.
431 BIOCHEMISTRY Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS E T Chouchani et al. SEE N&V R350
436 DNA REPAIR Transcript-RNA-templated DNA recombination and repair H Keskin et al.
44O BIOCHEMISTRY A cross-chiral RNA polymerase ribozyme
J T Sczepanski 1 & G F Joyce
SEE N&V P. 347
443 CANCER Discovery and characterization of small molecules that target the GTPase Ral
C Yan et al.
448 STRUCTURAL BIOLOGY Structures of bacterial homologues of SWEET transporters in two distinct conformations
Y Xu et al.
nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE
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