EDITORIALS
7 NATURAL RESOURCES The uncertain dash for gas Predictions of fracking's bounty may be on shaky ground
7 SCIENCE AND SOCIETY
Harsh reality
The postdoc's lot is not a happy one — and that needs to change
8 CLIMATE CHANCE
Look ahead
lt is prudent to research geoengineering strategies, even if they won't be used
WORLD VIEW
n Science should keep out
of partisan politics
Daniel Sarewitz
lt is too simplistic to demonize
the right and laud the left
SEVEN DAYS
12 THE NEWS IN BRIEF
HIV on the rise in Eastern Europe and Central Asia / Polio vaccinators killed in Pakistan /James Watson sells Nobel medal / UK chooses quantum hubs
15 INFECTIOUS DISEASE
Race to bring Ebola vaccine to the field gets under way
16 BIOENGINEERING
Investigations launched into artificial trachea work
18 PALAEONTOLOGY
Meet the fossils challenging
Archaeopteryx's status as the first bird
2O CLIMATE CHANCE
Researchers thrash out guidelines for geoengineering
21 MEDICAL RESEARCH
Initiative aims to träck off-label use of drugs to treat cancer
FEATURES
24 PHYSICS
Quantum computer quest
Thirty years of struggle are finally
bearing fruit for quantum computers
Sea-level rise and river engineering spell disaster, say Liviu Giosan, James Syvitski, Stefan Constantinescu &John Day
BOOKS & ARTS 34 MATHEMATICS
Set theory for six-year-olds
Alex Bellos
35 BOOKS IN BRIET
36 ROBOTICS Bottom-up innovation Noel Sharkey
CORRESPONDENCE
37 Conservation
policy debated /
New pasture plants — or invasive weeds
OBITUARY
3B Herman Eisen (1918-2014) Lisa Steiner & Hidde Ploegh
133 INDUSTRY SKILLS Boosting business A number of programmes exist to ease the transition from biomedical trainee
to management
I35 CAREER BRIEFS
TOOLBOX
131 ROBOTICS
The automated lab
The nature of research is changingas new software and advanced robotics begin to take care of the manual work
NEW ONLINE
39 Papers published this week at nature.com
NEWS & VIEWS
40 CELL EIETOOL/9A
Autophagy transcribed
Nuclear receptors control expression of lysosomal and autophagy genes Carmine Settembre & Andrea Ballabio
SEE LETTERS R108 & P.112
41 EARTH SCIENCE
Controls on isotopic gradients in rain Modelling depletion of heavy isotopes in rain as storms cross land
Katherine H Freeman
42 MICROBIOLOGY
A backup for bacteria
Norovirus infection restores immune
development in germ-free mice
Yao Wang & Julie K Pfeiffer
SEE LETTER R94
44 ASTROPHYSICS
Stars fight back
A massive galactic outflow of molecular
gas in a compact galaxy
Philip F Hopkins SEE LETTER R68
45 NEUROBIOLOGY
A molecular knife to dice depression A pathway involving 13-catenin and Dicer Proteins may mediate resilience Gerhard Schraff SEE ARTICLE P.51
46 TECHNOLOGY
Ultrafast imaging takes on a new design
Capturing non-repetitive events at
100 billion frames per second
Brian W Pogue SEE LETTER R74
48 BEHAVIOURAL ENADAMS Professional identity can increase dishonesty
Banking business culture may weaken employees' honesty norms
Marie Claire Villeval SEE LETTER P.86
49 DIABETES
The good in Tat
Fatty acids that enhance glucose uptake from blond in mice Deborah M Muoio &
Christopher B Newgard
ARTICLES
51 NEUROSCIENCE ß-catenin mediates
stress resilience through Dicer1/ A representation of single-shot ultrafast photography at 100 billion frames a second. Gao et al. use compressed imaging with a streak camera to video record non-repetitive transient events in two dimensions, with resolution down to tens of picoseconds.
PAGES 46 & 74
microRNA regulation
C Dias et al. SEE N&V P.45
56 STEM CELLS Deconstructing transcriptional heterogeneity in pluripotent stem cells
R M Kumar et al.
62 CELL BIOLOGY Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase J Steuber et al.
LETTERS
68 ASTROPHYSICS Stellar feedback as the origin of an extended molecular outflow in a starburst galaxy J E Geach et al. SEE N&V R44
7I SUPERCONDUCMITY Nonlinear lattice dynamics as a basis for enhanced superconductivity in YBa2Cu306.5 R Mankowsky et al.
74 TECHNOLOGY Single-shot compressed ultrafast photography at one hundred billion frames per second
L Gao,J Liang, C Li & L V Wang
SEE N&V P.46
79 MATERIALS SCIENCE Conductive
two-dimensional titanium carbide `clay' with high volumetric capacitance
M Ghidiu, M R Lukatskaya, M-Q Zhao,
Y Gogotsi & M W Barsoum
82 CUMATE Eastern Pacific tropical
cyclones intensified by EI Nino delivery of subsurface ocean hegt F-F Jin,J. Boucharel & 1-1 Lin
86 BEHAVIOURAL ECONOMICS Business culture and dishonesty in the banking industry
A Cohn, E Fehr & M A Marechal
SEE N&V P.48
90 PLANT SCIENCES Inhibition of cell expansion by rapid ABP1-mediated auxin effect on microtubules
X Chen et al.
94 MICROBIOLOGY An enteric virus can replace the beneficial function of commensal bacteria
E Kernbauer, Y Ding & K Cadwell
SEE N&V P.42
99 CELL BIOLOGY The ESCRT machinery regulates the secretion and longrange activity of Hedgehog
T Matusek et al.
104 CELL BIOLOGY Centriole amplification by mother and daughter centrioles differs in multiciliated cells
A A Jord et al.
I08 CELL BIOLOGY Transcriptional regulation of autophagy by an FXR—CREB axis
S Seok et al. SEE N&V P.40
112 CELL. 810100V Nutrient-sensing nuclear receptors coordinate autophagy M Lee et al. SEE N&V R40
116 CANCER TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein
S Bhatnagar et al.
12I NEUROSCIENCE Piezo2 is the major transducer of mechanical Torces for touch sensation in mice
SS Ranade et al.
126 NEUROSCIENCE Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel
S G Brohawn, E B Campbell
& R MacKinnon
nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE
***NEUWERTIG***keine Lesespuren***SEHR SCHÖN***
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