EDITORIALS
273 NEUROSCIENCE
What lies beneath
The shift towards biological targets in
psychiatric conditions is welcome
273 GENOMICS
How to get ahead
Realistic goals can inspire
rapid innovation
274 HISTORY
Past wisdom
The Nature Pastcast offers some
historical tips for future generations
WORLD VIEW
275 Fraudbuster with political antennae required
Colin Macilwain
David Wright's resignation raises tough questions for the US Office of Research Integrity
RESEARCH HIGHLIGHTS
276 SELECTIONS FROM THE
SCIENTIFIC LITERATURE
Orange makes you think /
High-mileage badgers / Overheated crops / Nanotubes boost leaves / Nanoprinting in 3D / Out of Africa, by mistake / More warming in Greenland
SEVEN DAYS
278 THE NEWS IN BRIEF
Illegal fires ravage Sumatra / Asian carp head north in the US / Gulf War illness eludes definition / Europe bans HFCs
399 RETRACTIONS
A clean slate
When things go wrong, it pays to act promptly to set the record straight
391 COLUMN
Strapped students
Susie Crowe
With postgraduate education so costly, prospective students need to think long and hard about whether it's for them
2B1 COSMOLOGY
Antarctic telescope spies evidence of gravitational waves
2B3 REGENERATIVE MEDICINE
Pressure mounts over methodology in acid-bath stem-cell papers
2B5 POLICY
France Cordova takes the heim at the National Science Foundation
2B6 ECOLOGY
Water set to retum to Colorado River delta
288 POLICY
NIH takes fresh tack an psychiatry trials
A unique US programme has pushed the cost of sequencing ever lower PAGE 294
29O NEUROSCIENCE Tuning the brain Researchers are hamessing deep brain stimulation to investigate problem neural circuits
297 TECHNOLOGY TRANSFER Industry-funded academic
inventions boost innovation
Brian D Wright Kyriakos Drivas, Zhen Lei & Stephen A Merrill
University of California data busts myths an licences, patents and citations
3OO RENEWABLE ENERGY
Back the renewables boom
Jessika E Trancik
Public-policy support is needed to keep
low-carbon technologies an track
The British Library salutes scientific
images in its first science exhibition
3O3 HUMAN EVOLUTION Just add water Richard G Roberts
3Oi BOOKS IN BRIEF
CORRESPONDENCE
3O6 Think big an medical data / Portuguese R&D is OK / Make forests count /Japan needs more autopsies
NEW ONLINE
307 Papers published this week at nature.com
NEWS & VIEWS
3O8 SPACE SCIENCE
Near-Earth space shows its stripes Explaining a structured feature of Earth's inner radiation belt Drew L Turner SEE LETTER P.338
309 GENETICS
Closing the distance on obesity culprits An intron containing obesity-associated SNPs is a long-range gene enhancer David U Gorkin & Bing Ren
SEE LETTER P.371
3I0 TECHNOLOGY
Photonics Illuminates the
future of radar
A fully photonics-based coherent
radar system
Jason D McKinney SEE LETTER R341
312 CELL BIOLOGY
The disassembly of death
Antibiotic inhibition of pannexin 1 channels deregulates apoptosis Christopher D Gregory SEE ARTICLE R329
3I3 BONE BIOLOGY
Vessels of rejuvenation
Type H endothelial cells induce angiogenesis and promote osteogenesis Ferdinand le Noble & Jos le Noble
SEE ARTICLE P.323 & LETTER P.376
ARTICLES
315 CANCER GENOMICS Comprehensive molecular characterization of urothelial bladder carcinoma The Cancer Genome Atlas Research Network
323 DEVELOPMENTAL 810100V Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone A P Kusumbe, S K Ramasamy
& R H Adams. SEE N&V R313
329 DRUG DISCOVERY Unexpected link between an Antibiotic, pannexin channels arid apoptosis
I K H Poon et al. SEE N&V P.312
LETTERS
335 COSMOLOGY The remnant of a merger between two dwarf galaxies
ON THE COVER
Seen change
The mouse visual system contains several functionally distinct parallel pathways linking the motion detecting cells of the retina to neurons in the superficial layers of primary visual cortex. Directional and orientation selectivity in the cortex appear to arise from the earliest stages of visual processing involving in motion detecting cells in the retina. PACE 358
in Andromeda II
N C Amorisco, N W Evans & G van de Ven
338 MAGNETOSPHERIC PHYSICS Rotationally driven `zebra stripes' in Earth's inner radiation belt
A Y Ukhorskiy et al. SEE N&V P.308
341 OPTICS AND PHOTONICS A fully photonics-based coherent radar system
P Ghelfi et al. SEE N&V P.310
346 ENVIRONMENTAL CHEMISTRY Sulphide oxidation and carbonate dissolution as a source of CO2 over geological timescales
M A Torres, A J West & G Li
35O EVOLUTION Melanosome evolution
indicates a key physiological shift within feathered dinosaurs
Q Li et al.
354 EVOLLITIONARY GENETICS The genomic landscape of Neanderthal ancestry in present-day humans
S Sankararaman et al.
358 NEUROSCIENCE A dedicated circuit links direction-selective retinal ganglion
cells to the primary visual cortex
A Cruz-Martin ,et al.
362 STEM CELLS Intestinal crypt
homeostasis revealed at single-stemcell level by in vivo live imaging L Ritsma et al.
366 IMMUNOLOGY I1-35-producing
B cells are critical regulators of immunity during autoimmune and infectious diseases
P Shen et al.
371 MOLECULAR BIOLOGY Obesity-associated variants within FTO form long-range functional connections with IRX3 S Smemo et al. SEE N&V P.309
376 DEVELOPMENTAL BIOLOGY Endothelial Notch activity promotes angiogenesis and osteogenesis in bone
S K Ramasamy, A P Kusumbe, L Wang & R H Adams SEE N&V R313
381 MOLECULARBIOLOGY Two independent transcription initiation codes overlap on vertebrate core promoters
V Haberle et al.
386 ADOENDUM Optical-field-induced current in dielectrics A Schiffrin et al.
387 ERRATUM Global carbon dioxide emissions from inland waters P A Raymond et al.
nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE
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