EDITORIALS
5 BIOMEDICAL RESEARCH Animal farm
Misrepresentation of addiction by animal-rights activists should not be allowed to derail research
6 IMMIGRATION Invisible borders
Free mobility of scientists is crucial
6 THE AMAZON
Trick of the Iight
Carbon in the balance and
photosynthesis out of the shadows
WORLD VIEW
7 China must protect high-quality arable land
Xiangbin Kong
Loss of food-producing land to urban growth threatens food security
RESEARCH HIGHLIGHTS
B SELECTIONS FROM THE
SCIENTIFIC LITERATURE
Prion
portraits / The Anglo-Saxon succession / Gene editing in a primate / US leads in global warming / Social lizards/ Galaxies that failed
SEVEN DAYS
1O THE NEWS IN BRIEF
Panama combats dengue with GM mosquitoes / Butterfly migration hits historic low / Cancer burden predicted to rise / AstraZeneca pulls out of neglected tropical diseases
121 TELECOMMUTING
No place like home
Researching from home can work but you need to manage your time — and maintain yoür profile
123 CAREER BRIEFS Adre •
13 CRIMINOLOGY
US launches bid to fix faulty forensics
14 IMMIGRATION
Visa problems dog scientists heading to the UK
16 CITIZEN SCIENCE
@Home computer projects lose their lustre
17 PUBLISHING
Elsevier opens journals to text mining
18 VITICULTURE
Ferment over move of gene bank for grapevines
19 SEMICONDUCTORS
Phosphorus version of graphene Shows promise for circuits
FEATURES
Climate change threatens a radical change to winter Sports PACE 20
24 BIOMEDICINE
The changing face of primate research
Fresh obstacles undermine European harmony on experiments using monkeys
6
27 CLIMATE ECONOMICS
Make supply chains climate-smart Anders Levermann
Networks of trade, production and transport must adapt to cope with floods and storms to come
31 BOOKS IN BRIEF
32 GEOLOGY Bedrock of China Xu Xing
33 O&A
The sound hunter
Acoustic engineering professor Trevor
Cox on the joys of 'sound tourism'
CORRESPONDENCE
34 The use of medical data / Planck Collaboration data / Carbon dioxide storage
OBITUARY
35 John Cornforth (1917-2013) Jim Hanson
NEW ONLINE
37 Papers published this week at nature.con NEWS & VIEWS
38 FORUM: MICROBIOLOGY
A talented genus
Biosynthetically diverse bacteria isolated from marine sponges Marcel Jaspars; Greg Challis SEE ARTICLE R58
39 CANCER
Interference identifies immune modulators
RNA-interference screening of T-cell gene activity in melanoma Lars Zender SEE ARTICLE R52
41 ATMOSPHERIC SCIENCE
Drought and fire change sink to source Factors that increase carbon emissions over the Amazon basin
Jennifer K Balch SEE LETTER P.76
42 IMMUNOLOGY
Oiling the wheels of autoimmunity Recognition of CD1a-bound skin oils by self-reactive T cells
Mitchell Kronenberg & Wendy L Havran
43 PARTICLE PHYSICS
Quarks are not ambidextrous Parity-symmetry breaking in electron—quark scattering experiments William J Marciano SEE LETTER P.67
44 ECOLOGY
Plant diversity rooted in pathogens Fungal pathogens determine negative density dependence in tropical forests Helene C Muller -Landau
SEE LETTER P.85
ARTICLES
47 PALAEOECOLOGY Fifty thousand years of Arctic vegetation and megafaunal diet
E Willerslev et al.
52 CANCER In vivo discovery of immunotherapy targets in the tumour microenvironment P Zhou et al. SEE N&V P.39
5B MICROBIOLOGY An environmental bacterial taxon with a large and distinct metabolic repertoire M C Wi/son et al. SEE N&V P.38
LETTERS
63 ASTROPHYSICS A cosmic web filament revealed in Lyman-a emission arounc a luminous high-redshift quasar S Cantalupo, F Arrigoni-Battaia,
J X Prochaska, J F Hennawi & P Madau
67 PARTICLE PHYSICS Measurement of
parity violation in electron—quark scattering
The Jefferson Lab PVDIS Collaboration SEE N&V P.43
71 QUANTUM PHYSICS An optical lattice
clock with accuracy and stability at the 10' level
BJ Bloom et al.
76 ATMOSPHERIC SCIENCE Drought sensitivity of Amazonian carbon balance revealed by atmospheric measurements
L V Gatti et al. SEE N&V R41
B1 ATMOSPHERIC CHEMISTRY Convective forcing of mercury and ozone in the Arctic boundary layer induced by leads in sea ice
C W Moore et al.
85 ECOLOGY Pathogens and insect
herbivores drive rainforest plant diversity and composition
R Bagchi et al. SEE N&V R44
89 PLANT EVOLUTION Three keys to the radiation of angiosperms into freezing environments
A EZanne et al.
93 PSYCHOLOGY Modelling the effects of subjective and objective decision making in scientific peer review I-U Park, M W Peacey & M R Munafö
97 POPULATION GENETICS Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
The SIGMA Type 2 Diabetes Consortium
1O2 STRUCTURAL BIOLOGY Structure of the
SecY channel during initiation of protein translocation
E Park et al.
1O7 STRUCTURAL 810LOGY Structures of the Sec61 complex engaged in nascent peptide translocation or membrane Insertion
M Gogala et al.
11I MOLECULAR 8I0L0GY Aprataxin resolves adenylated RNA—DNA junctions to maintain genome integrity
P Tumbale, J S Williams, M J Schellenberg TA Kunkel & R S Williams
116 STRUCTURAL BIOLOGY Crystal structures
of the Lsm complex bound to the
3' end sequence of U6 small
nuclear RNA
L Zhou et al.
Good tirnin.• g
The most precise atomic clock yet, based an multiple strontium atoms
PAGE 71
nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE
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