WORLD VIEW
267 WHO plans for neglected diseases are wrong
Mary Moran
Pilot projects will oller scant benefits and threaten to derail R&D
RESEARCH HIGHLIGHTS 26B SELECTIONS FROM THE SCIENTIFIC LITERATURE
Water-powered antifreeze / Windturbine generated lightning / Sugary drink data questioned / Cancer risk byassociation /The
Lpower of a soft touch / Whales head count
SEVEN DAYS
27O THE NEWS IN BRIEF
Stem-cell study under fire / Politicians rally to tackle poaching / China Moon rover down but not out / Long-distance neutrinos detected
397 INTERVIEWS En garde
For success in your interview, prepare and stay cool
399 CAREER BRIEFS
273 ENVIRONMENT
China offers incentives in bid to tackle air pollution
274 ASTRONOMY
Mystery of missing galaxy mass
resolved by gravitational lensing
276 OCEANOGRAPHY
Chinese project looks for weather clues in Pacific
277 POLICY
Swiss immigration vote puts strain on EU relationship
27B SPACE
Low expectations greet X Prize bid to land on Moon
279 ACADEMIC APPOINTMENTS Hunger strike exposes flaws in Nepal's higher-education system
2B4 SCIENCE IN COURT
Smart enough to die?
Questions are being raised over whether measures of intellectual ability used to assess convicts are appropriate
Axel Meyer & Jorge A Huete-Prez The planned Nicaragua Canal could prove to be an environmental disaster PAGE 287
29O HEALTH POLICY
How to regulate faecal transplants Mark B Smith, Colleen Kelly & Eric J Alm A call to treat stool as a tissue, not a drug, for changing the gut microbiome
BOOKS & ARTS
292 NUCLEAR ENERGY
Meltdowns, redux
Mark Peplow
293 BOOKS IN BRIEF
294 RESEARCH AND DEVELOPMENT No matter, try again
Anthony King
CORRESPONDENCE
295 'Carbon currency / Peer review / Drug-
resistant TB / A step too far for fiction
FUTURES 4O2 Coffee in end times Alvaro ZinosAmaro &Alex Shvartsman
NEW ONLINE
297 Papers published this week at nature.com
NEWS & VIEWS
298 ASTROPHYSICS
Lopsided stellar death
A look back at the centre of the Cassiopeia A supernova
J Martin Laming SEE LETTER P.339
299 REGENERATIVE BIOLOGY
Take the brakes off for liver repair Angiopoietin 2 coordinates hepatic-cell proliferation alter injury
Andrew G Cox & Wolfram Goessling
3OO CANCER
Persistente of leukaemic ancestors Premalignant clonal populations detected in acute myeloid leukaemia Nicola E Potter & Mel Greaves
SEE ARTICLE P.328
3O2 PLASMA PHYSICS
A promising advance in nuclear fusion Fusion-energy yield exceeds energy invested in fusion fuel
Mark Herrmann SEE LETTER P.343
3O3 MOLECULAR BIOLOGY
Protein binding cannot subdue a lively RNA
The dynamics of an early step in ribosomal assembly
Kathleen 8 Hall SEE ARTICLE P.334
3O4 AGEING
Genetic rejuvenation of old muscle Repression of a senescence pathway revives geriatric stem cells
Mo Li & Juan Carlos lzpisua Belmonte
SEE ARTICLE R316
REVIEW
3O7 PALAEOCLIMATE The rise of oxygen in Earth's early ocean and atmosphere T W Lyons, C T Reinhard
& N J Planavsky
ARTICLES
316 STEM CELLS Geriatric muscle stern cells switch reversible quiescence into senescence
P Sousa-Victor et al. SEE N&V P.304
322 STEM CELLS In situ identification of bipotent stem cells in the mammary gland
- wir
ON THE COVER
In it together
A bumblebee and honeybee collecting sunflower nectar. Emerging honeybee pathogens are shown to be infectious in an important wild pollinator, the bumblebee. This raises the prospect that crop pollination could suffer if the spread of these diseases is unchecked. PAGE 364
A C Rios, N Y Fu, GJ Lindeman &J E Visvader
328 CANCER Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
L I Shlush et al. SEE N&V R300
334 MOLECULAR BIOLOGY Protein-guided RNA dynamics during early ribosome assembly
H Kim et al. SEE N&V P.303
LETTERS
339 ASTROPHYSICS Asymmetries in corecollapse supernovae from maps of radioactive 'Ti in Cassiopeia A
B W Grefenstette et al. SEE N&V P.298
343 PLASMA PHYSICS Fuel gain
exceeding unity in an inertially confined fusion implosion
0 A Hurricane et al. SEE N&V R302
349 MATERIALS SCIENCE Exceptional ballistic transport in epitaxial graphene nanoribbons
J Baringhaus et al.
355 GEOCHEMISTRY Prodigious degassing
of a billion years of accumulated
radiogenic helium at Yellowstone
J 8 Lowenstern, W C Evans, D Bergfeld & A G Hunt
359 EVOLUTION Species coexistence and the dynamics of phenotypic evolution in adaptive radiation
J A Tobias et al.
364 MOLECULAR ECOLOGY Disease associations between honeybees and bumblebees as a threat to wild pollinators
M A Fürst, D P McMahon, J L Osborne, R J Paxton & M J F Brown
367 EVOLUTION Unidirectional pulmonary
airflow patterns in the savannah monitor lizard
E R Schachner, R L Cieri,J P Butler &C G Farmer
37I CANCER Landscape of genomic
alterations in cervical carcinomas A I Ojesina et al.
376 DRUG DISCOVERY Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada et al.
3B2 BIOTECHNOLOGY Selection and evaluation of clinically relevant AAV variants in a xenograft liver model
L Lisowski et al.
387 CELL BIOLOGY Convergent evolution of a fused sexual cycle promotes the haploid lifestyle
R K Sherwood, C M Scaduto, S E Torres & R J Bennett
391 STRUCTURAL BIOLOGY Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA H Hashimoto et al.
396 CORRIGENOUM Probabilistic tost estimates for climate change mitigation
J Rogelj, D L McCollum, A Reisinger,
M Meinshausen & K Riahi
396 CORRIGENDUM Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
S Yoshimoto et al.
396 CORRIGENOUM DWARF 53 acts as a repressor of strigolactone signalling in rice
L Jiang et al.
nature, THE INTERNATIONAL WEEKLY JOURNAL OF SCIENCE
***NEUWERTIG***keine Lesespuren***SEHR SCHÖN***
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