EDITORIAL
Open goal
International collaborations can help bolster the continent's ambitions
FEATURES
201 Stars of South American science Growth in resources and opportunity
202 South America by the numbers A continent quantified
Big players
The leading lights in Latin American research
7117 Homeward bound Repatriation efforts pay off
COMMENT
Capacity building: Architects of South American science
Eduardo Arzt, Gisella Orjeda, Carlos Nobre, Juan Carlos Castilla, Lino Baranao, Sidarta Ribeiro, Claudia Bifano, Jose Eduardo Krieger, Pablo C Guerrero & Mary T K Arroyo A continent-wide look at how the region can boost its science base
19 Fellowships: Turning brain drain into brain circulation
Torsten Wiesel & Jimena Sierralta Successful scholarships provide sound foundation for Latin American science
EDITORIALS
A growing problem
GM crops are no quick fix for quashing
herbicide-resistant weeds
187 REGENERATIVE MEDICINE Good practice
A systematic approach to stem cells will reap therapeutic benefits
WORLD VIEW
189 Jordan's stem-cell Iaw can guide the Middle East
Rana Dajani
Framework offers legal and ethical guidance for Islamic nations
RESEARCH HIGHLIGHTS
190 SELECTIONS FROM THE
SCIENTIFIC LITERATURE
Bee-friendly insecticide / Theia's geology / HIV activated / Plankton light / First author first / As the crow thinks
SEVEN DAYS
192 THE NEWS IN BRIEF
SOFIA telescope saved / Germany pulls out of Square Kilometre Array / NIH sets out BRAIN plan / Illinois bans microbeads
195 REGENERATIVE MEDICINE
Cell-replacement therapies back an the
•
agenda for Parkinson's disease
196 SPACE
US–Russian tensions prompt NASA
drive for space-station experiments
198 GENETICS
Public database challenges Myriad over genetic test for breast cancer
199 ACOUSTICS
Undersea signal offers lead in search for missing Malaysian airliner
303 COLUMN
A test that fails
Casey Miller & Keivan Stassun
Many US graduate-school entry tests
are not fit for purpose BOOKS & ARTS
216 /MV
The third culture Michael John Gorman
217
The nutrient hunter
Journalist Jo Robinson champions purple foods—wine included
CORRESPONDENCE
218 Darwin, Wallace and women / Safe synthetic biology /Joint funding / Otlet first with citation analysis
FUTURES
306 Face in the dark Deborah Walker
NEW ONLINE
219 Papers published this week at naturecom
NEWS & VIEWS
22O MATERIALS SCIENCE
Diamond gets harder
The synthesis of nanotwinned diamond James Boland SEE LETTER R250
221 PLANT BIOLOGY
Pass the ammunition
Herbivory-induced emissions are changed into weapons in nearby plants Mark C Mescher & Consuelo M
De Moraes
222 IMMUNOLOGY
When Iymphocytes run out of steam Familial immunodeficiencies caused by a lack of CTPS1
Andre Seillette & Dominique Davidson
SEE LETTER R288
224 PARTICLE PHYSICS
The hunt for Majorana
neutrinos hots up
Searching for the neutrinoless double-ß-decay process
David Wark SEE ARTICLE P.229
225 CANCER BIOLOGY
Enzyme meets a surprise target A histone modifier acts downstream of oncogenic K-Ras in the cytoplasm Marian M Deuker & Martin McMahon
SEE LETTER R283
226 GENE THERAPY
Repair and replace
An optimized gene-repair protocol for
haematopoietic stein cells
Alain Fischer SEE ARTICLE P.235
An explanation for the existence of optically Bark y-ray bursters. PAGE 247
Synthetic diamonds go from strength to strength. PAGE 250
ARTICLES
229 PARTICLE PHYSICS Search for Majorana neutrinos with the first two years of EXO-200 data
The EX0-200 Collaboration
SEE N&V R224
235 IMMUNOLOGY Targeted genome editing in human repopulating haematopoietic stein cells
P Genovese et al. SEE N&V P.226
241 MOLECULAR BIOLOGY Homologue engagement controls meiotic
DNA break number and distribution
D Thacker, N Mohibullah, X Zhu &S Keeney
LETTERS
247 ASTROPHYSICS Two y-ray bursts from dusty regions with little molecular gas B Hatsukade et al.
25O MATERIALS Nanotwinned diamond with unprecedented hardness and stability
Q Huang et al. SEE N&V R220
254 CLIMATE SCIENCE Increased frequency of extreme Indian Ocean Dipole events due to greenhouse warming WCaietal.
259 ECOLOGY Elevated CO2 further Iengthens growing season under warming conditions Melissa Reyes-Fox et al.
263 NEUROSCIENCE Emergence of reproducible spatiotemporal activity during motor learning
A J Peters, SX Chen & T Komiyama
268 STEM CELLS The unfolded protein response governs integrity of the haematopoietic stem-cell Pool during stress
P van Galen et al.
273 STEM CELLS Human embryonicstem-cell-derived cardiomyocytes regenerate non-human primate hearts JJ H Chong et al.
278 CANCER Therapeutic targeting of BET bromodomain proteins in castration-resistant
prostate cancer
I A Asangani et al.
283 CANCER SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
P K Mazur et al. SEE N&V R225
288 IMMUNOLOGY CTP synthase 1 deficiency in humans reveals its central rote in lymphocyte proliferation
E Martin et al. SEE N&V P.222
293 STRUCTURAL B10LOGY A Ctf4 trimer couples the CMG helicase to DNA polymerase ct in the eukaryotic replisome A C Simon et al.
298 BIOCHEMISTRY Quantitative flux
analysis reveals folate-dependent NADPH production
J Fan et al.
New projections of future Indian Ocean climate cycles. PAGE 254
***NEUWERTIG***keine Lesespuren***SEHR SCHÖN***
- Articlenumber:
- B00042458
- Weight:
- 400 gr
- Storage space:
- Z7_4_16